sbmlsim.examples.experiments.midazolam.experiments.mandema1992

Module Contents

Classes

Mandema1992

Mandema1992.
class sbmlsim.examples.experiments.midazolam.experiments.mandema1992.Mandema1992(sid=None, base_path=None, data_path=None, ureg=None, **kwargs)[source]

Bases: sbmlsim.examples.experiments.midazolam.experiments.MidazolamSimulationExperiment

Mandema1992.

Parameters:

  • sid (str) –

  • base_path (pathlib.Path) –

  • data_path (pathlib.Path) –

  • ureg (sbmlsim.units.UnitRegistry) –

datasets()[source]

Define dataset definitions (experimental data).

The child classes fill out the information.

Return type:

Dict[str, sbmlsim.data.DataSet]

simulations()[source]

Define simulation definitions.

The child classes fill out the information.

Return type:

Dict[str, sbmlsim.simulation.TimecourseSim]

simulation_mid()[source]

Mandema1992

  • midazolam, iv, 0.1 [mg/kg] (infusion over 15 min)

  • 1-hydroxy midazolam, iv, 0.15 [mg/kg] (infusion over 15 min)

  • midazolam, po, 7.5 [mg]

Return type:

Dict[str, sbmlsim.simulation.TimecourseSim]

fit_mappings()[source]

Define fit mappings.

Mapping reference data on observables. Used for the optimization of parameters. The child classes fill out the information.

Return type:

Dict[str, sbmlsim.fit.FitMapping]

figures()[source]

Figure definition.

Selections accessed in figures and analyses must be registered beforehand via datagenerators.

Most figures do not require access to concrete data, but only abstract data concepts.

Return type:

Dict[str, sbmlsim.plot.Figure]

figure_mid()[source]