sbmlsim.examples.experiments.midazolam.experiments.mandema1992

Module Contents

Classes

Mandema1992

Mandema1992.

class sbmlsim.examples.experiments.midazolam.experiments.mandema1992.Mandema1992(sid=None, base_path=None, data_path=None, ureg=None, **kwargs)[source]

Bases: sbmlsim.examples.experiments.midazolam.experiments.MidazolamSimulationExperiment

Mandema1992.

Parameters
  • sid (str) –

  • base_path (pathlib.Path) –

  • data_path (pathlib.Path) –

  • ureg (sbmlsim.units.UnitRegistry) –

datasets()[source]

Define dataset definitions (experimental data).

The child classes fill out the information.

Return type

Dict[str, sbmlsim.data.DataSet]

simulations()[source]

Define simulation definitions.

The child classes fill out the information.

Return type

Dict[str, sbmlsim.simulation.TimecourseSim]

simulation_mid()[source]

Mandema1992

  • midazolam, iv, 0.1 [mg/kg] (infusion over 15 min)

  • 1-hydroxy midazolam, iv, 0.15 [mg/kg] (infusion over 15 min)

  • midazolam, po, 7.5 [mg]

Return type

Dict[str, sbmlsim.simulation.TimecourseSim]

fit_mappings()[source]

Define fit mappings.

Mapping reference data on observables. Used for the optimization of parameters. The child classes fill out the information.

Return type

Dict[str, sbmlsim.fit.FitMapping]

figures()[source]

Figure definition.

Selections accessed in figures and analyses must be registered beforehand via datagenerators.

Most figures do not require access to concrete data, but only abstract data concepts.

Return type

Dict[str, sbmlsim.plot.Figure]

figure_mid()[source]